Miami, FL – May 19, 2020 ( NewsWire) —, a leading independent small cap media portal with an extensive history of providing unparalleled content for the Emerging Growth markets and companies, Mateon Therapeutics, Inc. (OTCQB: MATN).

To navigate through the >200 potential therapeutic and vaccine options for COVID-19, GEN, in an article titled “COVID-19: 200 Candidated and Counting”  has grouped the candidates into four broad categories based on their developmental and (where applicable) clinical progress. 

FRONT RUNNER – the most promising therapeutics/vaccines based on clinical progress, favorable data or both.

DEFINITELY MAYBE – earlier phases with promising partners, or more advanced candidates in development that have generated uneven data.

KEEPING AN EYE ON… – interesting technology, attracting notable partners, or both, but preliminary data.

TOO SOON TO TELL – longshots pending additional experimental and/or clinical data.

Among those is OT-101 – an interesting technology, attracting notable partners, or both.  Mateon therapeutics (OTCQB:MATN) is developing OT-101 against COVID-19 and recently filed an IND with US FDA to allow it to start clinical trial against COVID-19.  OT-101 targets not only viral replication but often-lethal clinical sequelae of COVID-19, including pneumonia and fibrosis—which according to Mateon gives its treatment an efficacy and safety index on par or superior to Gilead Sciences’ remdesivir. OT-101 has also shown broad efficacy against solid tumors across multiple Phase II oncology trials, including pancreatic cancer, glioblastoma, and melanoma (Study P001) and in high-grade gliomas (Study G004), the company said.

“I am encouraged that Alhelfawi M. [1] and Chen W. [2] put forth hypothesis that inhibition of TGF-β as treatment of COVID-19.”  said Dr. Vuong Trieu, CEO of Mateon Therapeutics.

[1] Alhelfawi M. Potential approach for fighting against corona virus disease. ASRJETS. 2020;66:127-144.

[2] Chen W. A potential treatment of COVID-19 with TGF-β blockade. International Journal of Biological Sciences. 2020;16(11):1954-1955. Doi: 10.7150/ ijbs.46891.

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