Is it to late to buy Moderna after posting 40 Percent gains last week ? For those who felt they missed the bus a major potential opportunity awaits in Avalon GloboCare with a sub 100 million dollar market cap and multiple shots on goal

Keep your eye on is Avalon GloboCare (NASDAQ:AVCO)

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According to Motley fool article Is it to late to buy Moderan After 40% gain “?  Moderna (NASDAQ:MRNA) offered investors a big buying opportunity over the past six weeks. Shares of the coronavirus vaccine maker dropped as much as 36% from their all-time high. At the same time, news has been positive. The company continued the rollout of its vaccine and announced enrollment in trials of booster candidates targeting variants of concern.Then, finally, the rebound Moderna investors were waiting for gradually happened. Over the past three weeks, the stock has climbed about 40%. In fact, today the shares are only a few dollars away from Wall Street’s average 12-month price estimate. Now, the question: Is it too late to buy Moderna shares? Let’s find out. 

Above the record high

From January 2020 through January of this year, Moderna stock has dropped significantly three times. And each time, it recovered and climbed above its previous record high. It looks like that now may be happening for the fourth time. This may be a pattern of investors locking in profits, then repurchasing shares at a lower price — and newcomers jumping aboard too. 

Moderna has secured supply agreements worldwide for at least 800 million doses. That means those doses can fully vaccinate about 400 million people. And that means those countries likely would order the booster dose to complete the vaccinations of their citizens. Moderna hasn’t said how much each country is paying for its vaccine. But we can use the price paid by the U.S. as a guide. That’s $15 a dose. The 400 million people I just mentioned will need a booster, so that could generate $6 billion for Moderna.  Considering these elements, is Moderna a buy at these levels? My answer is “yes.” It’s possible Moderna shares will go through another lull down the road. It’s possible longtime investors will sell some shares to lock in profits.

But overall, I expect Moderna stock to climb higher over time. In the near term, a booster and expansion into the teen market can offer a lift. Beyond that, the company’s two dozen pipeline programs make me optimistic. Next to market may be a cytomegalovirus (CMV) vaccine — the candidate is set to enter phase 3 this year. (CMV is a common virus that is worrisome for pregnant individuals or people with compromised immune systems.)    

As big pharma races to save millions of lives there is a smaller less known “sleeping giant” in the CAR-T space developing advanced S-layer technology with limitless applications in the key development of an intranasal vaccine.  S-Layer  “surface layer” technology is used to develop an intranasal vaccine that attaches to the mucosal membrane CEO Dr. David Jin pointed out. “We see our vaccine candidate as a complement to any injectable vaccines in clinical trials, because it could provide first-line immune protection at the virus’s entrance site”. Adding a coat of an S-layer onto solid surfaces can greatly improve the function of a therapeutic, vaccine, or device. The S-layer allows enhanced efficiency and interaction of targeted proteins and molecules for better function.

Avalon GloboCare is in the process of establishing a state-of-the-art research facility, the Christian Doppler Laboratory, located on the BOKU campus in Vienna, Austria, under the scientific leadership of Professor Eva-Kathrin Ehmoser, the Head of BOKU’s Institute for Synthetic Bioarchitectures and Professor Uwe Sleytr, a member of the Austrian Academy of Sciences. In connection with the new facility, Avalon and BOKU have signed a Memorandum of Understanding (MOU) to jointly apply for a matching research grant from the prestigious Christian Doppler Laboratory Foundation. Avalon also has research being done in MIT (Massachusetts Institute of Technology), the UNRLS (University of Natural Resources and life sciences in Australia), Weill Cornell Medicine in New York City and the Lu Daopei Medical Group in China, which has the country’s top ranked hematology and bone marrow transplant program 

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In the December 2020 issue of Nature’s Biopharma Dealmakers, Avalon’s President and CEO, David Jin, M.D., Ph.D., highlighted Avalon’s ongoing scientific and clinical developments including a first-in-human trial of a mucosal, intranasal vaccine against SARS-CoV-2 that is planned for early 2021. Dr. Jin also described the company’s innovative, allogeneic mesenchymal stromal cell (MSC) therapy candidate, CB-MSC-1, which possess unique anti-inflammatory and immunomodulatory activities, as well as AVA-001, Avalon’s third-generation CAR T cell therapy that has shown robust activity in patients with relapsed, refractory B cell acute lymphoblastic leukemia in a Phase 1 trial (Avalon feature in Biopharma Dealmakers).

“We are excited and motivated to join forces with the researchers at BOKU to drive innovation. We have already begun a collaboration on the mucosal SARS-CoV-2 vaccine and are moving quickly to establish additional joint research endeavors to bring about innovative technologies and new medicines to patients,” said Dr. Jin.

Avalon GloboCare, is a young, $100 million market cap company that has arguably some of the brightest minds in cell-based technology who have a competitive advantage with their “S-Layer” technology in a vaccine market that is expected to grow to approximately 93.billion by 2026 according to Forbes business . This small cap biotechnology company is working towards the goal of changing the way we fight the devastating effects of diseases that relentlessly attack our immune systems by using our own bodies against us. In the first quarter of 2020, Avalon GloboCare successfully completed a phase 1 first-in-human clinical study of AVA-001 in China for the treatment of relapsed refractory B cell acute lymphoblastic leukemia (R/R B-ALL). 90% of R/R B-ALL patients achieved complete remission with one dose and within one month of treatment, and then proceeded to a curative-intent allogeneic bone marrow transplant.  With more upcoming catalysts in early 2021, it is safe to say that there is a large potential upside in AVCO’s stock is currently trading at its 52 week know at 1.00 in change , as the market is anticipating updates on their progress on multiple clinical trials, leaving the question most investors are asking themselves.” When will Avalon GloboCare (NASDAQ:AVCO) take off ?”


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